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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKP2 All Species: 14.55
Human Site: S320 Identified Species: 32
UniProt: Q13309 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13309 NP_005974.2 424 47761 S320 V H L D L S D S V M L K N D C
Chimpanzee Pan troglodytes XP_001147537 379 42771 K279 L S D S V M L K N D C F Q E F
Rhesus Macaque Macaca mulatta XP_001093834 422 47441 S318 V H L D L S D S V M L K T D C
Dog Lupus familis XP_546346 749 81658 S645 V H L D L S D S V M L K N D C
Cat Felis silvestris
Mouse Mus musculus Q9Z0Z3 424 47748 S320 I R L D L S D S I M L K N D C
Rat Rattus norvegicus Q9QZH7 276 30442 S177 L L E Q L N I S W C D Q V T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001007983 443 49750 V341 H L D L S D S V M L K P E C F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036659 499 55071 A375 N L I R L N I A G C R R V L F
Honey Bee Apis mellifera XP_395497 484 54314 L384 S C P D I I E L D L S D C T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780472 456 51238 E333 L N L G G Y R E K L Q N Q D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49286 360 39891 I261 G L Y Y C R N I T D R A M Y S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 91.9 52.3 N.A. 86.3 23.5 N.A. N.A. 64.1 N.A. N.A. N.A. 30 27.8 N.A. 31.3
Protein Similarity: 100 89.3 94.5 54.6 N.A. 92.9 36.7 N.A. N.A. 74.4 N.A. N.A. N.A. 50.9 50.6 N.A. 50
P-Site Identity: 100 0 93.3 100 N.A. 80 13.3 N.A. N.A. 0 N.A. N.A. N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 20 93.3 100 N.A. 93.3 33.3 N.A. N.A. 13.3 N.A. N.A. N.A. 33.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 20 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % A
% Cys: 0 10 0 0 10 0 0 0 0 19 10 0 10 10 37 % C
% Asp: 0 0 19 46 0 10 37 0 10 19 10 10 0 46 0 % D
% Glu: 0 0 10 0 0 0 10 10 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 28 % F
% Gly: 10 0 0 10 10 0 0 0 10 0 0 0 0 0 0 % G
% His: 10 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 0 10 10 19 10 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 10 0 10 37 0 0 10 % K
% Leu: 28 37 46 10 55 0 10 10 0 28 37 0 0 10 0 % L
% Met: 0 0 0 0 0 10 0 0 10 37 0 0 10 0 10 % M
% Asn: 10 10 0 0 0 19 10 0 10 0 0 10 28 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 10 10 19 0 0 % Q
% Arg: 0 10 0 10 0 10 10 0 0 0 19 10 0 0 0 % R
% Ser: 10 10 0 10 10 37 10 46 0 0 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 10 19 0 % T
% Val: 28 0 0 0 10 0 0 10 28 0 0 0 19 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 10 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _